Animals die in experiments very often. If they don't die they usually get injured or very sick.
Cruelty is also a big problem, including forcing animals to do tricks in circuses, and killing them if they don't do a trick right. Or microvaving animals.
I also think a huge problem is when people compare someone to an animal, in a bad way. Animals aren't dumb, crazy, ugly, mean, messy, dirty, inappropriate, or otherwise bad.
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